What is nmn? NMN stands for nicotinamide mononucleotide, which is the precursor to NAD+, the coenzyme that powers cellular metabolism. It’s a natural compound that can be found in foods like edamame, broccoli and avocado at a concentration of about 1 mg per 100g. It’s also available as a supplement in the form of nicotinamide riboside, or NR.
Is NMN good or bad?
Both NMN and NR are converted into NAD in the body. Studies have shown that NMN is beneficial for the health of the liver, muscles and skin. It can prevent metabolic diseases including diabetes and heart disease, reduce inflammation and improve eye health, libido and fertility in women. It can even extend lifespan in mice.
NR and NMN increase NAD+ levels in the body, which can help reduce age-related declines in mitochondrial function. They can also boost insulin sensitivity and improve cellular signaling in people with prediabetes and obesity. They can also protect against metabolic syndrome by reducing the build-up of fat in the liver and improving lipid and glucose metabolism.
Unlike NAD, which can be taken orally as a powder, NMN isn’t well-absorbed through the gut. However, a new technology called liposomal delivery can overcome this obstacle. It’s a process that encapsulates NMN in fatty “shells” similar to the cell membrane. This allows for faster absorption and prevents degradation by stomach acid. Some supplements such as Youngr NMN, which contains antioxidants and sirtuin activators, are formulated with this technology. They’re more expensive than traditional oral supplements, but they offer better bioavailability and are considered safe to take long-term.